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Mohassel Lab

Johns Hopkins School of Medicine

Department of Neurology, Neuromuscular Division

Pathology Building 635/636

Our Mission

  • Understand pathogenic mechanisms of monogenic neuromuscular diseases

  • Identify therapeutic targets   

  • Conduct proof-of-concept preclinical studies

  • Enable and conduct early-phase clinical trials of candidate therapies

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Current Projects

  • Collagen VI-related muscular dystrophy 

  • Serine palmityoltransferase (SPT)-related ALS  

  • Cell-based therapies for Duchenne muscular dystrophy 

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Disease Models

  • Patient-derived fibroblasts

  • iPSC-derived cells 

  • Transgenic mouse models 

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